In the USA, the drug is officially approved by the FDA for the treatment of intestinal strongyloidosis, onchocerciasis, as well as in the form of external forms for pediculosis and rosacea. Beyond these indications, the use of ivermectin is limited.
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New research 2024-2025
Recent data show that interest in ivermectin remains high, but the focus of research is shifting.:
- Epidemiology. Health Affairs (2025) published an analysis of three million prescriptions in the United States: the majority of prescriptions were in the southern states, and some were prescribed outside of official indications.
- Dermatology. The Journal of Investigative Dermatology (2025) noted that ivermectin cream is able to influence the skin microbiome in patients with rosacea.
- Neuroscience. A preclinical study (2024) showed that ivermectin can enhance dopaminergic activity, a potential interest for models of Parkinson’s disease.
- Public health. In 2024, WHO recommended mass campaigns with a single dose of ivermectin in regions with a high prevalence of strongyloidosis.
Ivermectin remains an indispensable drug in parasitology and dermatology. The new data emphasize that its use must strictly comply with the indications, and promising areas (neuroscience, oncology) still remain at the level of laboratory or review studies.
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